Y combinators investment wishlist 2025

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Published on May 15, 2025
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This is a list from Y Combinator showing startups they want to invest in the summer of 2025.

They include:

1. Full-Stack Al Startups
Why sell Al tools when you can build an entire business around them? Think Al-powered law firms or clinics that outpace traditional ones.

2. Designers as Founders
Designers, it's your time to shine! Use your eye for detail and user empathy to launch startups that people love to use.

3. Voice Al Revolution
Tired of robotic phone menus? Create Al that handles customer calls so naturally, people won't know it's not human.

4. Al in Scientific Research
Bring Al to the lab bench. Help scientists accelerate discoveries in chemistry, biology, and materials science with smarter tools.

5. Al Personal Assistants
Turn to-do lists into done lists. Build Al that doesn't just remind you but actually completes tasks on your behalf.

6. Al for Government Automation
Help governments save money and time by automating paperwork and processes with Al solutions.

7. Public Safety Tech
Develop tools like smart cameras and data systems that assist law enforcement in solving crimes more efficiently.

8. Next-Gen Manufacturing
Reimagine factories with automation and robotics, making manufacturing faster, cheaper, and closer to home.

9. Stablecoin Infrastructure
Build the backend systems that enable businesses and banks to use digital currencies seamlessly

10. LLMs for Chip Design
Use Al to design better, more efficient computer chips, speeding up innovation in hardware.

11. Al-First Fintech
Create financial tools powered by Al that offer smarter budgeting, investing, and lending solutions.

12. Space Infrastructure Startups
As space becomes more accessible, develop the logistics and support systems that make satellite launches routine.

13. Al-Aided Engineering Tools
Design intuitive engineering software that leverages Al to simplify complex tasks for professionals.

14. Empowering Non-Al Jobs
Focus on building tools that enhance jobs Al can't replace, supporting roles that require a human touch.

Here's some takeaways Greg Isenberg has about these:

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